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Alfonsina GATTUSO - Professori Associati

Alfonsina GATTUSO

Professori Associati

Fisiologia (BIOS-06/A)

Contacts
Reception Hours

Friday: 12:30 -13:30 pm, or by appointment via email

Education:    
1991: Master Degree in Biological Science, University of Calabria. Thesis in General Physiology, title:  "Effetti dei cardiopeptidi atriali sul cuore di un cefalopode, l'Octopus vulgaris L."
1992: Professional qualification of Biologist 
1994: PhD in Animal Biology, University of Calabria. Thesis in General Physiology, title: "Endotelio endocardico e performance miocardica nel cuore di rana". 

Academic Position
15/11/95-15/02/96: Technical consultant (art. 26), Pharmaco-Biology Dept, University of Calabria. 
01/04/1996 – 30/06/1996: Scientific collaboration contract (project CEE AIR 1-CT 92-0186).
07/01/1997-31/08/2001: Permanent Technical Assistant, Dept. of Cell Biology, University of Calabria.
1998: “Cultore della materia” of General Physiology.
01/09/2001: Researcher/Assistant Professor of Physiology (SSD BIO/09), Faculty of di S.M.F.N., UNICAL
01/09/2004-present: Permanent Researcher/Assistant Professor of Physiology (SSD BIO/09).
 

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Education 1991: Degree in Biological Science, University of Calabria. Thesis in General Physiology, title: "Effetti dei cardiopeptidi atriali sul cuore di un cefalopode, l'Octopus vulgaris L ." 1994: PhD in Animal Biology, University of Calabria. Thesis in General Physiology, title: "Endotelio endocardico e performance miocardica nel cuore di rana". Post-doctoral Experience 1995-1996: Contract Technical Assistant, Dept. Pharmaco-Biology, University of Calabria. 1997-2001: Permanent Technical Assistant, Dept. of Cell Biology, University of Calabria. 1998: “Cultore della materia” of General Physiology, Faculty of Mathematical, Physical and Natural Sciences, University of Calabria Present position: 1/9/2001-present: Permanent Researcher/Assistant Professor of General Physiology, Department of Cell Biology, Faculty of Mathematical, Physical and Natural Sciences, University of Calabria 2002-present: Member of the Doctoral Committee in Animal Biology, University of Calabria Scientific membership: Italian Society of Cardiovascular Research (SIRC) Italian Society of Physiology (SIF) Main research activity and scientific interests - Cardiac function of non-mammalian vertebrates (fish and amphibians). Cardiac hormones, nitric oxide and signaling. Role the endocardial endothelium (EE), as sensor and transducer of physical and chemical luminal stimuli. Effects of chemical (neurotransmitters, gasotransmitters, neuropeptides, nitrite anions, endothelin, natriuretic peptides, Chromogranin A-derived peptides, Selenoproteins, aquatic contaminants) and physical (hemodynamic load, hypoxia) factors on the heart mechanics and transductional pathways activated
Position: Assistant Professor/Researcher of Physiology (SSD BIO/09), Department of Biology, Ecology, and Earth Sciences (DiBEST). Address: Organ and Systems Physiology laboratory, Ponte Pietro Bucci, 6C, University of Calabria, 87036 Arcavacata di Rende (CS), Italy Phone: +39 0984 492905 E-mail: alfonsina.gattuso@unical.it Education: 1991: Degree in Biological Science, University of Calabria. Thesis in General Physiology, title: "Effetti dei cardiopeptidi atriali sul cuore di un cefalopode, l'Octopus vulgaris L." 1992: Professional qualification of Biologist 1994: PhD in Animal Biology, University of Calabria. Thesis in General Physiology, title: "Endotelio endocardico e performance miocardica nel cuore di rana". Academic Position 15/11/95-15/02/96: Technical consultant (art. 26), Pharmaco-Biology Dept, University of Calabria. 01/04/1996 – 30/06/1996: Scientific collaboration contract (project CEE AIR 1-CT 92-0186). 07/01/1997-31/08/2001: Permanent Technical Assistant, Dept. of Cell Biology, University of Calabria. 1998: “Cultore della materia” of General Physiology. 01/09/2001: Researcher/Assistant Professor of Physiology (SSD BIO/09), Faculty of di S.M.F.N., UNICAL 01/09/2004: Permanent Researcher/Assistant Professor of Physiology (SSD BIO/09). Affiliations - Società Italiana di Fisiologia (SIF) - Società Italiana di Ricerche Cardiovascolari (SIRC) - U.O. of University of Calabria (prof. T. Angelone) of Istituto Nazionale di Ricerche Cardiovascolari (INRC). - Referee for: MDPI Journals, Nitric Oxide-Biology and Chemistry, Current Medicinal Chemistry, Cardiovascular Research, AIMS Medical Science, American Journal Physiology (Regulatory and Integrative and Comparative Physiology), Environmental Science and Pollution Research, Experimental Gerontology, Biology Open. - External referee for ERC 2014 Starting Grant Call. - Review Editor per Frontiers in Physiology (section Vascular Physiology). Research activity and methodologies Main scientific interests are in the field of the cardiac physiology of non-mammalian vertebrates (amphibians and fish) in terms of both basic performance and humoral control. Early studies discovered the key role played by endocardial endothelium, through the release of Nitric Oxide, as a sensor and transducer of autocrine-paracrine-endocrine luminal stimuli in avascular hearts. Main results have highlighted the effects of both chemical (neurotransmitters, gasotransmitters, neuropeptides, nitrite anions, endothelin, natriuretic peptides, Chromogranin A-derived peptides, Selenoproteins, pollutants) and physical (hemodynamic load, hypoxia) factors on the heart mechanics of mammals (rat) and non-mammals (amphibians and fish), as well as transductional pathways activated. Isolated and perfused cardiac preparations; image and data analysis system for determining ventricular volume changes during the cardiac cycle. Partecipation to Funded Research Projects 1993-1996: Research program CEE n. AIR1-CT92 0186 “Improvement of the nutritional value, growth and resistance to stress of eels and sturgeon by controlled dietary lipids and conditions during intensive aquaculture" in cooperation with University of Birmingham (Prof. E.W. Taylor, Dott. David McKenzie), Copenaghen (Prof. J. Steffensen). Referent of Unical U.O.: Prof. Bruno Tota. 1995-present: Research Projects founded by the University of Calabria (ex 60%). 1996-2014: PNRA (Programma Nazionale di Ricerche in Antartide), O.U. University of Calabria: PdR 2013/AZ1.20; PdR 2010/A1.08; PdR 2004/1.03; PdR 1999/2c.1.1; PdR 1996/1.1. 1998-2000: BIOTECHNOLOGY PROGRAM (MURST-CNR, 95/95): Title: "New development of species and technologies for the aquaculture. Subtitle 4F: Marine and environmental biotechnologies". in cooperation with Prof. C. Storelli, University of Lecce and Prof. G. Zummo (University of Palermo). Referent of Unical U.O.: Prof. Bruno Tota 2000-2001: Research program “Indicatori precoci di insufficienza cardiaca: applicazioni in Medicina di nuove biotecnologie”; sottotitolo: “Controllo nitrergico della performance cardiaca: aspetti evolutivi”, G.I.M.E.C. (Centro interuniversitario per le ricerche genetiche immunologiche, metaboliche ed emodinamiche sulle cardiovasculopatie), University of Naples. Referent of U.O. of Unical: Prof. Bruno Tota. 1999: Project “Cardiovascular function in Salmo salar with infectious salmon anaemia (ISA): putative role of nitric oxide” LSF program (Large Scale Facility for Marine Pelagic Food Chain Research), U.E. N. ERBFMGECT950013, in cooperation with Institute for fiskeri-og marinbiologi, University of Bergen (Norway). 2000: Project “Cardiovascular function in Salmo salar with infectious salmon anemia (ISA): putative role of nitric oxide” contratto U.E. HPRI-1999-CT-00056 (Bergen Marine Food Chain Research Infrastructure) in cooperation with Institute for fiskeri-og marinbiologi, University of Bergen (Norway). 2003: Progetti di Rilevante Interesse Nazionale (PRIN 2003, Code: 2003051588), PI: TOTA Bruno (UNICAL). Title: LE VASOSTATINE: NUOVI PEPTIDI REGOLATORI DELLA FUNZIONE CARDIACA E DELLA MUSCOLATURA LISCIA. 2008: Progetti di Rilevante Interesse Nazionale (PRIN 2008, Code 2008Y8B2XH), PI: GATTUSO Alfonsina (Università della CALABRIA). Titolo: LA CATESTATINA (CROMOGRANINA A 352-372): UN NUOVO COMPONENTE MOLECOLARE NELLA CONNESSIONE CERVELLO-CUORE. 2011-2013: PON Ricerca e Competitività 2007-2013 - Asse I - Aree scientifico-tecnologiche”. Title: “Modelli sperimentali biotecnologici integrati per lo sviluppo e la selezione di molecole di interesse per la salute dell'uomo” (PON01_00937/1), partners: University of Bari, Metapontum Agrobios, CNR and DLVSystem s.r.l. Scientific Coordinator: Prof. Cesare Indiveri (UNICAL). 2019-2021: PON Ricerca e Innovazione 2014-2020, DEMETRA (DEvelopment of MatErial and TRAcking technologies for the safety of food) Project – “Sviluppo di tecnologie di materiali e di tracciabilità per la sicurezza e la qualità dei cibi” – cod. ARS01_00401. Scientific Coordinator: Prof. Riccardo Barberi (Unical). 2021-2023: Project: “SI.F.I.PA.CRO.DE. Sviluppo e industrializzazione farmaci innovativi per terapia molecolare personalizzata PA.CRO.DE.” PON ARS01_00568, finanziato dal PON Ricerca e Innovazione 2014-2020 nell’ambito dell’Asse II “Progetti tematici”, azione “Cluster”. Scientific Coordinator: Prof . Sebastiano ANDO’ (Unical). 2021-2024: Project “Centro Ricerche ed Infrastrutture Marine Avanzate in Calabria (CRIMAC)”, Fondo FSC 2014-2020 - Piano Stralcio “Ricerca e Innovazione 2015-2017» – Programma Nazionale Infrastrutture di Ricerca (PNIR). Titolo: Blu_Ca_Prod: Blue Economy of Calabrian coasts: biocoenotic characterization, analyses and exploitation of innovative aquaculture productions. 2023-2025: Project “Tech4You- Technologies for climate change adaptation and quality of life improvement”, codice identificativo ECS 00000009, CUP H23C22000370006, Piano Nazionale di Ripresa e Resilienza, Missione 4, Componente 2, Investimento 1.5. Delegato per lo Spoke 2: prof. Anna Pinnarelli (UNICAL). 2023-2027: Project “CAL.HUB.RIA (CALabria HUB per Ricerca Innovativa ed Avanzata”, codice identificativo T4-AN-09, CUP H53C22000800006, Piano Operativo Salute, Traiettoria 4, Azione 4.1 “Creazione di Hub delle Scienze delle Vita”. Scientific Coordinator: Prof.ssa Eleonora Bilotta (UNICAL). 2023: Project “Piano Regionale per le zone allocate per l’acquacoltura a mare – AZA; (AVAM-AZA)”, identificativo n. 02/ASA/22, C.U.P. J56D23000000009. Scientific Coordinator: Prof. Emilio Sperone (UNICAL). 2023: Project "Creazione di isole di ripopolamento per la pesca sostenibile lungo le coste dell'alto Tirreno cosentino" -CIRPES, identificativo 32/RBC/20, C.U.P. J66D20000400009. Scientific Coordinator: Prof. Emilio Sperone (UNICAL). 2023-2025: Progetti di Rilevante Interesse Nazionale (PRIN 2022, Codice 20228XHTBZ). Coordinatore/PI: Prof. T. VERRI (UniSalento). Titolo: SOLUTE CARRIER 15 MEMBER A4): INTEGRATED IN VITRO-IN VIVO ANALYSIS AND FUNCTIONAL CHARACTERIZATION. Referente Scientifico Unical: Prof. Sandra IMBROGNO. Institutional Assignments 2021-present: Quality Assurance delegate of the Department (D.R. 692, 5/5/2021). 2017-present: Member of the Committee for Stakeholders Dialogue - Bachelor's and Master's degree programmes (Biology, Technology in Biological Sciences, Health Biotechnology). 2017-present: Member of the Doctoral Committee in Life Science and Technology, University of Calabria. 2013-present: Member of the Review Group for Annual and Cyclical Review Report of Bachelor's and Master's degree programmes (Biology, Technology in Biological Sciences, Health Biotechnology). Formerly: - Vice-Coordinator of Degree courses in Biology (First Degree and Master Degree), Technology in Biological Sciences (First Degree), and Health Biotechnology (Master Degree) (from 15/01/2016 to 31/10/2019). - Member of the Executive Committee, Dept. of Biology, Ecology, and earth Sciences (DiBEST) (2015-2016; 2017-2020). - Member of the Doctoral Committee in “Animal Biology”, University of Calabria (2003-2011) - Member of the Doctoral Committee in “Life Sciences", University of Calabria (2012). - Member of the Doctoral Committee in “Scienze della Vita", University of Calabria (2013, 2017, 2018). Member of: - Evaluation Committee for the admission to the PhD program in Animal Biology (XXI ciclo) (D.R. n. 2599-9/09/2005). - Selection Committee for recruitment of Permanent Researcher position (SSD BIO/09), Faculty of SMFN, University of Napoli Federico II (D.R. N.4079-3/11/2005). - Evaluation Committee for Postdoc Research fellow (SSD BIO/09), Pharmaco-Biological Dept. (D.R. N.100-19/01/2006). - Evaluation Committee for Postdoc Research fellow (SSD BIO/10), Cell Biology Dept. (D.R. N.2104 - 12/07/2006). - Selection Committee for Academic recruitment for Permanent Researcher position (SSD BIO/09), Faculty of SMFN, University of Palermo (D.R. N. 5189-23/11/2007). - Evaluation Committee for Postdoc Research fellow (SSD BIO/09), Cell Biology Dept. (D.D. N.7-27/07/2012). - Evaluation Committee for Postdoc Research fellow (SSD BIO/09), Project “DEMETRA – Sviluppo di tecnologie di materiali e di tracciabilità per la sicurezza e la qualità dei cibi”, PON ARS01_00401 (D.D. N. 157-21/10/2020). - Evaluation Committee for Research fellowship, Project “DEMETRA – Sviluppo di tecnologie di materiali e di tracciabilità per la sicurezza e la qualità dei cibi”, PON ARS01_00401 (D.D. N. 158-21/10/2020). - Evaluation Committee for Research fellowship, Project “DEMETRA – Sviluppo di tecnologie di materiali e di tracciabilità per la sicurezza e la qualità dei cibi”, PON ARS01_00401 (D.D. N. 83/2021-15/11/2021). TEACHING ACTIVITY: - Principles of Experimental Biology, Degree in Biological Science (AA 2001/02-2002/03): - Laboratory of Cell and Organism Biology, Degree in Biological Science (AA 2002/03) - Comparative Physiology, Degree in Natural Sciences (AA 2002-2003) - In vitro techniques for cardiac function assessment, PhD course in Animal Biology, University of Calabria (AA 2002/03). - Physiology of marine organisms, Degree in Biological Science (AA from 2002/03 to 2010/11) - Principles of Comparative Physiology, Degree in Natural Sciences (AA from 2002/03 to 2010/11) - Physiology of adaptations, Master Degree in Natural Sciences (AA from 2003/04 to 2008/09) - Vertebrate Evolution and Adaptation (module “Comparative Physiology”) Master Degree in Biodiversity and Natural Systems (AA from 2009/10 to 2011/12) - Environmental Animal Physiology, Master Degree in Biodiversity and Natural Systems (AA 2012-13) - Physiology, Degree in Biological Science and Technology (AA 2012/13 - present) Lectures and laboratory practicals at “Scuola di Specializzazione all’Insegnamento Secondario (SSIS)”, University of Calabria: - Didattica della Biologia dell’uomo (AA 2005/06) - Laboratorio di didattica della Biologia e Fisiologia dell’uomo (AA 2006/07) - Biologia dell’uomo ed educazione alla salute (AA 2007/08) - Didattica della Biologia dell’uomo ed educazione alla salute (AA 2008/09) TUTORSHIP (undergraduate and graduate students) 2002- present: tutor and co-tutor for ungraduated students of Degree courses in Biological Science and Natural Sciences (DM 509/99), in Biology (First Degree and Master Degree), Technology in Biological Sciences (First Degree), and Health Biotechnology (Master Degree) (DM 270/04). 2008: Scientific Referent of the research project “Analisi proteomica sistematica e differenziale in colture cellulari di cardiomiociti e cellule endoteliali di ratto”, for the “Programma Integrato di Voucher e Borse per l’alta formazione-POR CALABRIA 2000-2006”, Dept. of Cell Biology, University of Calabria. Title: Analisi proteomica sistematica e differenziale in colture cellulari di cardiomiociti e cellule endoteliali di ratto. 2012-2013: Scientific Referent for Post-Doc research grant (SSD BIO/09), Dept. of Cell Biology. Title: “Effetti cardiovascolari della Cromogranina A (CGA) e dei peptidi CGA-derivati di nuova sintesi”. 2014-present: tutor for curricular internships. 1/11/20-31/03/21: Scientific Referent for a post-graduate scholarship for research activities, project PON ARS01_00401, “DEMETRA – Sviluppo di tecnologie di materiali e di tracciabilità per la sicurezza e la qualità dei cibi”. TUTORSHIP (PhD programs) 2006-2008: PhD program in Animal Biology (XXI cycle). Title: Azioni cardiache della Catestatina in Rana esculenta (Dr. Sandra Barbieri). 2012-2015: PhD program in Scienze della Vita (XXVIII cycle). Title: Effect of different formulations of magnesium chloride, used as anaesthetic agents, on the performance of the isolated heart of Octopus vulgaris (Dr. Chiara Pugliese). 2022-2025: PhD program in Life Science and Technologies (XXXVIII ciclo). Dr. Alessia Caferro.
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Contacts
Reception Hours

Friday: 12:30 -13:30 pm, or by appointment via email