Curriculum Vitae
Name Serena Dato
Place Of Birth: Reggio Calabria, Italy
Tel.+39/0984/492930
E-Mail serena.dato@Unical.It
Nationality Italian
Education
1995 High School Degree, Liceo Scientifico “L. Da Vinci”, Reggio Calabria, With Final Mark 60/60.
2002 Degree In Biological Sciences (22/3/2001) At University Of Calabria, With Final Mark 110/110 Cum
Laude, (Equivalent Of Bsc + Ms)
2002 Abilitation In Biology, Obtained At University Of Calabria (11/1/2002).
004 Phd In Molecular Bio-Pathology, Obtained At University Of Calabria On 17/12/04, Discussing A Thesis
Entitled: “The Genetics Of Longevity: From Case Control Studies To The Genetic Demographic Approach”.
Work Experiences
Actual Position : Associate Professor in Genetics (Bio/ 18)18), from 1 st October 2022 to Nowadays At University Of Calabria, DiBest.
1 st September 2006- 30 th September 2022: Assista nt Professor In Genetics (Bio/18) At University Of Calabria.
April 2017: Abilitation As Associate Professor In Genetics (Art. 16, Comma 1, Legge 240/10)
Nov 2002-Nov 2004 Phd In Molecular Bio Pathology At University Of Calabria
Nov 2004-July 2006 Research Assistant At University Of Calabria
Nov 2004-Oct 2007 Responsible For The Sampling Of Long Lived Sibpairs In Calabria Region, Sourthern Italy, In The Frame Of The Eurpoean Project Geha (Genetics Of Healthy Aging) Project ( Fp6, Priority 1: Life Sciences, Genomics And Biotechnology For Health, Proposal N°: Fp6 503270).
Scientific Manager For The Local Unit In Geha Project
Personal Skills And Competences
Language Skills: Mother Tongue: Italian
Other Languages: English
(Reading: Excellent; Writing: Good; Spoken Interaction: Good)
Work Skills:
Bioinformatic Analyses
Dna Sequencing
Snp Genotyping With Sequenom And Illumina Platform, Including: Quality Controls, Alignment, Read Counts Summarization, Variant Calling.
Snps Data: Population Stratification Detection, Linkage Disequilibrium, Association Analyses (Single Snps, Epistatic Interaction Analyses By Mdr), Family-Based Analysis, Geneious, Mendel
Functional Annotation: Eqtl, Meqtl; Enrichment And Pathway Analysis Using
Gene Ontology, Kegg, Reactome.
Population Genetics Metrics (Gene Diversity, Genetic Distances And Phylogenetics Trees, Fst, And Neutrality Tests).
Biostatistics: Summary And Descriptive Metrics, Parametric And Non-Parametric Tests, Linear And Logistic Univariate And Multivariate Regression Models, Principal Component Analysis, Survival Analysis
Optimal Use Of The Main Statistical Analysis Programmes (Spss, Matlab) And Genetic Softwares(Come Mendel, Plink, Haploview)
Research Activity
2019-Current: Study Of Genetic Determinants Of Human Aging and Longevity; Analysis of the genetic contribution in age-related diseases
2001/2004 Study Of Genetic Determinants Of Human Aging, Through Genetic-Demographic Approaches.
March 2003 Winner Of The Prize “Progetto Giovani Ricercatori” At University Of Calabria Research Title: “Gene Expression Analysis Of Sirte 3 Gene In Linfoblasts Cultures From Young And Centenarian Samples: Analysis Of Gene Expression Changes During Cellular Aging.
Oct 2003/March 2004 Rtn (Research Training Network, Eu) Fellow At The Laboratory Of Survival And Longevity Of The Max Planck Institute For Demographic Research, Rostock, Germany.
Research Project On The Development Of A Genetic-Demographic Model For Analyzing Genetic Variability In Human Longevity, Under The Supervision Of Prof. J. Vaupel.
2005/2007 Study Of Longevity In Families Of Centenarians And Nonagenarian Sibpairs. Genotyping Of Markers In Candidate Genes For Longevity And Transmission Analyses In Pedigrees Recruited In The Project Echa (Fp5, Key Action “The Aging Population”- 2001/2004).
Oct 2008/ Sept 2009 Visiting Researcher At The Danish Aging Research Center- -Institute Of Public Health- Unit Of Epidemiology-University Of Southern Denmark. Collaboration To The Project “Study Of Genetic Determinats Of Human Longevity N The 1905 Danish Cohort” With Prof. Kaare Christensen.
Membership in Phd Schools
2006/2008 Member Of PhD School In Molecular Bio-Pathology, Department Of Cell Biology, University Of Calabria.
2008/2012 Member Of PhD School In Operative Research, Department Of Cell Biology, University Of Calabria.
2013/Nowadays Member Of PhD School In Life Sciences, Department Of Biology, Ecology And Earth Sciences, University Of Calabria.
Teaching Activity
2006/2008 Teacher For The Course In Human Genetics For Biologists, Faculty Of Natural, Physical And Matematical Sciences, Unical.
2009/2010 Teacher For The Course In Multifactorial Genetics For The Bachelor Degree In Biological Sciences, Department Of Biology, Ecolgy And Earth Sciences
2010/2012 Teacher For The Course In Genomics For The Master Degree In Biology, Department Of Biology, Ecology And Earth Sciences
2013/Nowadays Teacher For The Course In Genetics For The Master Degree In Bio-Technology, Department Of Biology, Ecology And Earth Sciences.
Other Teaching Experiences:
Internship Support Activities
Supervisor Of 50 Bachelor And 15 Md Thesis
Supervisor Of 2 Phd Thesis.
Current National and International collaborations:
The Danish Twin Registry and Epidemiology, Biodemography and Biostatistics, Department of Public Health, University of Southern Denmark (Prof K Christensen, Prof. Mette Soerensen, Prof. B. Jeune).
Translational Genomics Research Institute (TGen), Phoenix (Arizona) (Prof. Ignazio Piras).
Department of Nutrition Sciences, University of Alabama at Birmingham, USA (Prof.ssa Maria De Luca).
MRC Laboratory for Molecular Cell Biology, University College London, UK (Prof. Adolfo Saiardi).
Scuola di Bioscienze e Medicina Veterinaria, Università di Camerino (Prof. Valerio Napolioni)
Dipartimento di Biologia e Biotecnologie "L. Spallanzani", Università degli Studi di Pavia (Prof. Francesco Lescai).
Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo (Prof. Sonya Vasto).
Department of Medicine, University of Salerno (Prof. Annibale Puca).
Regional Neurogenetic Centre, ASP, CZ (Dr.ssa Amalia Bruni, Dr. Raffaele Maletta).
Reviewer Activities:
Aging (Dodr) (If: 5.179)
Aging Cell (If: 7.627)
Genes (If: 3.311)
Experimental Gerontology (If: 3.08)
Oxidative Medicine And Cellular Longevity (If: 4.868)
Rejuvenation Research (If: 3.22)
Mechanism Of Aging And Longevity (If:3.603)
Annals Of Human Genetics.
Editorial Activities:
2019- Current: Editorial Board Member Of Genes.
Jan-Dec 2019: Guest Editor For Genes. Special Issue: Genetic Determinants Of Human Longevity
Jan 2020- Nowadays : Guest Editor For Frontiers In Genetics. Special Issue: “Omics Of Human Aging And Longevity In The Post Genome Era: From Single Biomarkers To System Biology Approaches.
May 2018 – Co-Editor Of The Book: Interdisciplinarità, Complessità E Questioni Epistemiche, With Pio Colonnello, Amalia Cecilia Bruni, Giuseppe Passarino. In Filosofia E Scienza, 2017, Roma, Aracne.
Congress Participations:
1) 3rd International Congress Of Biogerontology: "The Biogerontological Basis Of Preventive Medicine And Geriatric Practice" - Montecatini Terme (Pt) - 8-11 Novembre 2002.
2) “Rtn Workshop On New Approaches For Longevity And Mortality Research” - San Francesco Conference Room, Alghero (Cg) - 13-14 Febbraio 2004.
3) Statistical Genetics Short Course - Featuring Mendel And Simwalk - Ucla Campus, Los Angeles, California, Usa - 22-28 Agosto 2004.
4) 56th Advanced Course “ Working With The Hapmap” – Wellcome Trust Genome Campus – Hinxton, Cambridge, Uk – 31 Luglio-2 Agosto 2006.
5) Geha Training Workshop On “Mitochondrial Dna Variability And Complex Traits”- Department Of Cell Biology- University Of Calabria, Rende, Italy-26-28 Marzo 2007.
6) Geha 3rd Annual Meeting-Nencki Institute Of Experimental Biology Pas- Warsaw- Poland- 28-29 Giugno 2007.
7) Geha Training Course On Genetic Data Analysis- Linkage Analysis Methods For The Geha Project, Mpidr Rostock, Germany, 11–13 Novembre 2007.
8) Geha 4th Annual Meeting- Grottaferrata (Rome)-Italy- 30 Giugno-2 Luglio 2008.
9) 6th European Congress Of Biogerontology, , Nh Conference Center Leeuwenhorst, Noordwijkerhout, The Netherlands- 30 Novembre-3 Dicembre 2008.
10) Agi Meeting - Associazione Genetica Italiana- 7-9 Settembre 2017, Cortona (Arezzo, Italy).
11) Congresso Nazionale CARDIOLOGIA E SPORT;“ Quando l’attività sportiva è un alleato e quando è un nemico del cuore”; Rende 10 – 11 Giugno 2022
12) XVI FISV CONGRESS, 3R: Research, Resilience, Reprise; Reggia di Portici (NA), 14-16 Settembre 2022
13) Joint Meeting AGI_SIMAG 2023, 14-16 SETTEMBRE 2023, Cortona (Arezzo, Italy)
Congress Communications
1) “3rd World Aging and Rejuvenation Conference (ARC-2021)”- venue September 20-22, 2021, Barcelona, Spain. Online webinar participation. Talk ““The contribution of Inositol pyrophosphate - metabolizing enzymes (IP6K3 and IPMK) gene variability to human aging and diseases”, Sessione “Healthy Ageing”.
2) “Longevita' in buona salute: una questione di geni e di stile di vita” – Cotronei (kr)- 23 febbraio 2019. Talk: “Genetica dell’invecchiamento e longevità”
3) AGI 2017 – Cortona (Ar) 7-9 Sept 2017. Talk: “The genetic component of human longevity: new insights from pathway-based snp-snp interactions”.
4) “Geha One-Day Training Meeting. Nencki Institute Of Esperimental Biology- Warsaw- Poland- 28-29 June 2007. Talk: “Study Of Heteroplasmy In The Mtdna Control Region Encompassing The C150t Mutation In Geha Sibpairs And Controls”.
5) “Geha 4th Annual Meeting”-Grottaferrata (Roma)-30 June-2 July. Talk: “Heteroplasmy Levels In Mtdna Loop Are Genetically Correlated In Sibpairs Selected For Longevity”.
6) “Echa Final Meeting” - Capo Suvero, Gizzeria Lido (Cz) - 18 December 2004. Talk: “Genotyping Concordant/Discordant Cousin Pairs”.
Proceedings papers
Montesanto A, Dato S, Soerensen M, Lagani , Passarino G, Christensen K, Christiansen L. UCP3 polymorphisms, hand grip performance and survival at old age. In proceedings of the Joint Meeting,
Agi-sibv-siga, 19-22 settembre 2011, Assisi (PG), Italy
Dato S, Mari V. Genetics of longevity. Abstracts of de Senectute: Age and Health Forum. Catanzaro, Italy. December 5-7, 2009. BMC Geriatr. 2010;10 Suppl 1(Suppl 1): A1-113, L1-81.
Bellizzi D., Di Cianni F., Covello G., Dato S., De Benedictis G. Two Genes Related To Aging And Longevity (Sirt3 And Psmd13) Share A Common Bidirectional Promoter. Atti Del Convegno Ŗrd International Conference On Functional Genomics Of Ageing", Palermo Italy, 29 Marzo -1 Aprile 2006.
Book chapter contributions:
1) Cosa ci rende umani. Analisi comparativa di geni coinvolti nello sviluppo cognitivo nel genoma dell’uomo e di primati non umani, di Dato S, Passarino G, Vigna M. (2017). In: Interdisciplinarità, complessità e questioni epistemiche. vol. 15, p. 21-40, a cura di A. C. Bruni, P. Colonnello, S. Dato, G. Passarino; Roma: Aracne Editrice, ISBN: 978-88-255-0083-7, doi: 10.4399/97888255008372.
2) Evoluzione dei linguaggi, dei geni e delle popolazioni umane, di Dato S, Vigna, M, Passarino G. Uno sguardo interdisciplinare. In: Interdisciplinarità, complessità e questioni epistemiche. vol. 15, p. 21-40, a cura di A. C. Bruni, P. Colonnello, S. Dato, G. Passarino; Roma: Aracne Editrice, ISBN: 978-88-255-0083-7, doi: 10.4399/97888255008372.
3) Aspetti genetici dell’evoluzione del linguaggio umano: un’analisi comparativa e interdisciplinare di Dato S, Vigna, M, Passarino G. In: Interdisciplinarità, complessità e questioni epistemiche. vol. 15, p. 21-40, a cura di A. C. Bruni, P. Colonnello, S. Dato, G. Passarino; Roma: Aracne Editrice, ISBN: 978-88-255-0083-7, doi: 10.4399/97888255008372.
4) Different components of frailty in the aging subjects-The role of sarcopenia. di Crocco P, Iannone, F, Dato, S, Rose, G, Passarino, G. In Human Aging: From Cellular Mechanisms to Therapeutic Strategies – Academic Press- USA; doi:10.1016/c2019-0-04856-x. pp.1-364.
Complete List Of Publication At: https://pubmed.ncbi.nlm.nih.gov/?term=dato+s
Membership Of Scientific Societies:
Agi (Associazione Genetica Italiana)
Eshg (European Society Of Human Genetics)
Summary Of Scientific Achievements
(March 2023, From Google Scholar)
Https://Orcid.Org/0000-0003-2589-7929
Papers: 63
Total Citations: 3340
H Index: 32
I10-Index: 46
